In clinical trials, Progesterone, a female sex hormone, shows promise in treating Traumatic Brain Injury (TBI). TBI occurs when a sudden trauma causes injury to the brain. This could be the result of a blow to the head, or when a sharp object pierces the skull, and penetrates the brain tissue. TBI symptoms include continuous headaches, dizziness, blurred vision, ringing in the ears, memory loss, difficulty concentrating, bad taste in the mouth, fatigue, and lethargy.
Besides being a female sex hormone, Progesterone is also a neurosteroid, which is essential for brain development and repair of neurones in the brain. “We found encouraging evidence that progesterone is safe in the setting of TBI, with no evidence of side effects or serious harmful events,” says David Wright, MD, assistant professor in the Department of Emergency Medicine at Emory and lead author of the study.